Pilomatrixoma is a rare benign skin tumor which was initially described by Malherbe and Chenantais in 1880. It occurs at any age, but predominantly around 10 years old and are usually asymptomatic except palpable mass, Multiple pilomatrixomas are rare, as in 3.5% of reported cases of pilomatrixomas. In Korea, a few reports of pilomatrixomas were made, but those of multiple pilomatrixomas associated were very rare. One case of multiple pilomatrixomas associated with pain and tenderness in 12-year-old male is presented with review of relevant literatures.