Abstract

The author has examined the influence of emotional cold stressor upon the liver cells and adrenal glands of rats histopathologically. Consequently the author has drawn the following conclusions : 1. In view of the fact that the characteristic histopathological changes brought about by the non-specific harmful agents mentioned above are common to the liver cells, and that the changes are closely connected with the function of adrenal cortex, these changes should be looked upon as a manifestation of the reaction of organism upon the stress, manely, as a part of General Adaptation Syndrome (Selye). 2. The Stress has a stimulating effect not only on the zona fasciculata, but also on the zona glomerulosa. However, the manifestation of the stimulating effect upon both zones shows discrepancy of time.