Primary angiosarcoma of the breast occurring usually in young women is a rare but distinctive clinical and pathologic entity. It is an extremely aggressive tumor usually with unfavorable prognosis which exhibits recurrences and hematogenous metastases. In August, 1977, we experienced a case of angliosarcoma of the right breast in 33 year old woman who had a progressively enlarged, palpable mass in the inner upper quadrant of the breast. Clinical data and histopathological findings of this case were discussed with a brief review of literature on this entity.