Actinomycosis is chronic, progressive, bacterial or fungal disease, more suppurative than granulomatous, with a marked proclivity for forming abscesses and sinus tracts. The causative agent is a branching, gram-positive, anaerobic or microaerobic organism, apparently parasitic but bacteria-like in most of its characteristics. The main species responsible for the disease in man is Actinomyces israelii, a normal inhabitant of the gastrointestinal tract. Recently authors are experienced two cases of actinomycosis, each of which occurred at mandible and anterior aspect of thigh. A brief review of literature pertinent to these case was done.