Abstract

The present study was undertaken to assess the effects of storage on the stability of plasma immunoglobulins(IgG, IgA, IgM and IgD) in ACD stored blood after periods of storage up to 12 weeks at 4℃. 1) Blood was drawn from 5 healthy volunteer donors into acid-citrate-dextrose(ACD) anticoagulant containers and placed in the blood bank refrigerator. Plasma immunoglobulins were measured on all samples initially and every week up to 12 weeks of storage at 4℃. Plasma immunoglobulins were measured by single radial immunodiffusion method. 2) Results of analyses are presented and discussed. The coefficient of variation of test samples is compared with that of standard quality control data (IgG: 8.8%, IgA: 7.9%, IgM: 9.5% and IgD: 9.3%) 3) No significant differences were found in the concentrations of immunoglobulins compared with the initial concentrations at the 3rd week (expiration date) and the 12th week.