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The Korean Journal of Pathology 1982;16(1): 98-102.
기관지에 발생한 과립상 세포 종양 -증례보고-
Granular Cell Tumor of Bronchus
Granular cell tumor is relatively uncommon lesion appearantly peculiar to man with uncertain histogenesis. It arises most commonly in the tongue but the bronchus is rarely the site of this tumor. The present paper is a report on a case of granular cell tumor arising from the left lower lobe bronchus. 29-year old Korean women was admitted to BNUH on November, 1978, because of productive cough, hemophtysis and chest pain for 15 years. She was well until 15 year of age, when she had been treated with drugs, under the diagnosis of pulmonary tuberculosis for 2 years with no effect at local clinic. The physical examination on admission revealed moist coarse rales on the left lower lung field. An X-ray films of the chest showed radioopaque density with peumonic infiltration on the left lower lobe. Bronchogram revealed bronchiectasis at this lesion. Under the diagnosis of bronchiectasis, the left pneumonectomy was performed. Grossly the left lung was not remarkable except for a palbable small firm mass on the left lower lobe. On section, there was a small peduncleated polypoid gray white mass within the left bronchus with partial obstruction of its lumen. The neoplasm extended through the wall of the bronchus to peribronchial tissue and adjacent lung parenchyma. It measured about 2㎝ in the long diameter. Histologically the neoplasm was consisted of diffuse sheets of large oval to polygonal cells that had abundant fine granular cytoplasm and a small central to eccentric nuclei. The cells were disposed in small groups, separately form each other by delicated fibrous stroma. The full thichness of the underlying wall of the bronchus, peribronchieal tissue and even adjacent pulmonary tissue were diffusely infiltrated by tumor cells.
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