The authors recently experienced Samlonella osteomyelitis of the right humeral neck. The patient was a 37-year-old male, who had no clinical history of suffering from typhoid fever. The laboratory data, such as CBC, ESR, and widal test were normal. X-ray revealed round radiolucent area on the right humeral neck about 3㎝ in diameter. Culture revealed the etiological agent, Salmonella typhi. He was treated with curettage and continuous irrigation. Chloramphenicol was used for 20 days and ampicillin and septrim for 5 weeks.