| Home | E-Submission | Sitemap | Contact Us |  

The Korean Journal of Pathology 1983;17(3): 288-296.
정상부인 및 질염환자의 질내 균종에 관한 비교 연구
A Comparative Study of Bacterial Flora in Normal and Vaginitis Women
There are many reports on the distribution of normal flora in the vagina and the causative agents of vaginal inflammatory disease. The most commonly encountered organisms are known to be doderlein bacillus which plays a major role in the cleanliness of the vagina. The other organisms frequently found in healthy as well as inflammatory vagina are staphylococci, streptococci, hemophilus species, diphtheroid bacilli, coliforms, fungi, and others. However the incidences of lactobacilli on the cultures show some differences between several authors. Also it is considered to be significant relationship of lactobacilli to the vaginal acidity as well as to vaginitis. Therefore this study is aimed to observe the distribution of bacterial flora in normal group and vaginal cleanliness and pH, were analysed. The results of the study were as follows; 1) The flora on direct vaginal smear in normal and vaginitis was graded according to the presence of doderlein bacilli. Cases of normal group reveals mostly grade I (38%), while vaginitis group reveals mostly grade II (42%). 2) 88% of the cases isolate on the culture of the vaginal flora in normal group and 90% of the cases isolate on the culture of the vaginal flora in vaginitis group. 3) The incidence of staphylococci, coliform group, hemophilus species and monilia in vaginitis group are higher than that of normal group, while the incidence of lactobacilli and diphtheroid bacilli in vaginitis group are lower than that of normal group. 4) 56% in normal group and 43% in vaginitis group grew on general culture media with 5-10% Co2. But 79% in normal group and 58% in vaginitis group of lactobacilli grew on selective media with 5-10% Co2, Also cultivation of vaginal lactobacilli on selective media gives satisfactory yield. 5) The distribution of vaginal pH values in vaginitis group reveals higher pH values than that of normal group. In the normal, vaginal pH values were distributed 4-5 predominantly, and vaginal pH values of vaginitis were distributed 5-6 predominantly. 6) Lower the pH value of vagina, lower the grading of direct vaginal smear, and also increase the positivity of lactobacilli on selective media.