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The Korean Journal of Pathology 1984;18(2): 203-208.
소뇌에 발생한 상의모세포종 1예 보고
A Case Report of Ependymoblastoma
Ependymoblastomas arise from the cells lining the central ventricular system and the central canal of spinal cord. It is very rare type of primitive glioma which has a characteristic regular pattern of solid cords around thin walled blood vessel, forming an arrangement of perivascular pseudorosetters and/or typical ependymal rosettes in local areas. It is rapidly growing and diffusely infiltrating tumor, especially in childhood. Over than half of all ependymoblastomas occur in young ages. Ependymoblastomas have been described a few different terms and different definitions by several authors, such as malignant ependymoma, anaplastic ependymoma, ependymoma grade Ⅲ and Ⅳ, and so on. We experienced one case of primitive glioma which can be regarded as ependymoblastoma arising at the carebellar vermis in eight year old boy, who has complained of vomiting, ataxia and diplopia. The signs of increased intracranial pressure, i. e. papilledema and separation of suture Line in brain scanning were noted. The submitted sepecimen (S-83-1785) consisted of five fragments of pinkish brown irregular shaped tissue, 1 cm in the length of the largest mass. Microscopically the tumor mass was composed of relatively uniformed glial cells, arranged in perivascular area, forming multiple layer and vascular changes with partly necrotic granulomatous area. Te individual cells are small round with hyperchromatic nuclei and significant number of mitotic figures. The above clinicopathologic findings are compatible with ependymoblastoma.
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