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HOME > J Pathol Transl Med > Volume 33(8); 1999 > Article
Case Report Chronic Hepatitis in the Idiopathic Hypereosinophilic Syndrome: A case report .
Kyeong Hee Kim, Hae Joung Sul, Sung Chul Jun, Dae Young Kang
Journal of Pathology and Translational Medicine 1999;33(8):624-626
DOI: https://doi.org/
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Department of Pathology, College of Medicine, Chungnam University, Daejeon 301-040, Korea.

Chronic hepatitis associated with the idiopathic hypereosinophilic syndrome has been very rarely reported worldwide. Recently, we experienced a case of chronic hepatitis with piecemeal necrosis as the clinical feature of the idiopathic hypereosinophilic syndrome. The patient was a 49-year-old woman who complained of a mild fever, nausea, vomiting, and pain in the right upper quadrant. The eosinophil count of peripheral blood increased up to 14,020/microliter (64% of WBC). Liver biopsy specimen showed severe porto-periportal inflammation with marked eosinophilic infiltration and ballooning degeneration of hepatocytes. Corticosteroid therapy significantly normalized the eosinophil count of peripheral blood.

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