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The Korean Journal of Cytopathology 1997;8(1): 52-56.
Oxyphilic Papillary Carcinoma of the Thyroid in Fine Needle Aspiration .
Young Min Kim, Gyung Yub Gong, On Ja Kim
Department of Pathology, Asan Medical Center, Ulsan University College of Medicine.
Oxyphilic (H rthle) cells have abundant eosinophilic granular cytoplasms and occur in both benign and malignant neoplasms of the thyroid gland. Most published studies described mainly oxyphilic tumors of follicular type, and reports on oxyphilic papillary thyroid carcinomas are rare. The oxyphilic variant of papillary carcinoma differs from the classic papillary carcinoma in its more aggressive biological behavior. We report a case of oxyphilic papillary carcinoma exhibiting exclusively oxyphilic cells in a follicular pattern without papillary structures. The pattern of papillary carcinoma was confirmed by fine needle aspiration material and lymph nodal metastasis, both of which revealed typicaled papillary structures with characteristic nuclear features, psammoma bodies, and oxyphilic cytoplasm.
Key Words: Papillary carcinoma; Thyroid; H rthle(Oxyphilic) cell; Fine needle aspiration