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The Korean Journal of Pathology 2002;36(4): 271-273.
Intestinal Metastasis of Osteosarcoma Presenting with Intussusception: A Case Report.
Seong Ho Yoo, Min A Kim, Kyu Joo Park, Joon Koo Han, Sang Hoon Lee, Chong Jai Kim, Eui Keun Ham
1Department of Pathology, Seoul National University College of Medicine, Seoul, Korea. cjkim@plaza.snu.ac.kr
2Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
3Department of Radiology, Seoul National University College of Medicine, Seoul, Korea.
4Department of Orthopedic Surgery, Seoul National University College of Medicine, Seoul, Korea.
ABSTRACT
Metastatic osteosarcoma most commonly affects the lungs and other bones. Intestinal intussusception caused by metastatic osteosarcoma is very rare. We report a case of metastatic osteosarcoma of the intestine in a 39-year-old female. She underwent surgical resection of the left femur due to osteosarcoma and received additional chemotherapy 3 years ago. Pulmonary metastasis was found two years later and the patient complained of abdominal pain, nausea and vomiting after 8 months following excision of the lung nodules. Abdominal computed tomography revealed intussusception with a suspected polypoid mass in the distal portion of the jejunum. The histologic findings of the resected bowel were those of osteosarcoma. This is the first case of documented intestinal metastasis of osteosarcoma in Korea. It is suggested that the tumor metastasis to the small intestine should be considered in patients with previous osteosarcoma, when the patient presents with acute abdominal symptoms and intussusception.
Key Words: Osteosarcoma-Neoplasm Metastasis-Intussusception