E-submission
Articles
- Page Path
- HOME > J Pathol Transl Med > Volume 38(2); 2004 > Article
- Case Report Minimal Deviation Adenocarcinoma, Mucinous Type, of the Uterine Cervix: Report of a Case with Extensive Metastasis to the Uterine Corpus and Bilateral Adnexae.
- Eundeok Chang, Eunjung Lee, Kyoungmee Kim, Okran Shin, Youngmi Ku, Heejung An, Changsuk Kang
-
Journal of Pathology and Translational Medicine 2004;38(2):121-125
DOI: https://doi.org/
2Department of Radiology, The Catholic University of Korea, College of Medicine, Uijongbu, Korea.
3Department of Pathology, Pundang CHA Hospital, Pochon CHA University, Seoul, Korea.
- 1,620 Views
- 16 Download
- 0 Crossref
- 0 Scopus
Abstract
Minimal deviation adenocarcinoma is an extremely well differentiated variant of cervical adenocarcinoma, and is frequently misdiagnosed due to its benign-looking histopathological features. A 38-year-old woman was diagnosed as having had a minimal deviation adenocarcinoma in the cervix, metastasizing to the uterine body and bilateral adnexae. She had a history of right salpingo-oophorectomy 3 years ago, and was diagnosed as having a mucinous cystadenoma. Histologically, the tumor cells were so well-differentiated that they appeared to be almost the same as those of the non-neoplastic cervical glands. Similar glands were found in both ovaries and in the left fallopian tube. PAS staining showed a negative or apical positive pattern in the endocervical-like glands. Immunohistochemical studies for CEA, ER/PR, cytokeratin 20, and p53 were negative, but positive for cytokeratin 7. The HPV DNA microarray test was negative. Clinically, this proved to be an advanced, biologically aggressive disease.
Cited- Related articles
-
