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The Korean Journal of Pathology 2004;38(5): 330-332.
Toxoplasmic Lymphadenitis with Toxoplasma Bradyzoites: A Case Report.
Hwa Eun Oh, Insun Kim
1Department of Pathology, Kwandong University College of Medicine, Myongji Hospital, Goyang, Korea. ohe11@hanmail.net
2Department of Pathology, Korea University College of Medicine, Seoul, Korea.
Toxoplasmic lymphadenitis is the most frequently observed clinical form of acquired toxoplasmosis. It is diagnosed by observing the characteristic histopathology, performing serologic tests and demonstrating the organisms. However, detection of the organisms in lymph node section is rarely accomplished. We demonstrate a case of a toxoplasmic lymphadenitis of a 40-year-old man with bradyzoites. The histopathologic findings of the lymph nodes showed reactive follicular hyperplasia associated with the presence of irregular clusters of epithelioid histiocytes, usually located in the cortical and paracortical zones, and monocytoid B cell proliferation. We demonstrated the bradyzoites of Toxoplasma gondii with periodic acid-Schiff (PAS)-stain, and serologic testing showed positive Ig-G and Ig-M toxoplasma antibodies.
Key Words: Toxoplasma Lymphadenitis; Bradyzoites; PAS stain