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The Korean Journal of Pathology 2004;38(5): 353-356.
Mixed Ductal-Endocrine Carcinoma of the Pancreas: A Case Report.
Ok Jun Lee, Yong Mee Cho, Hyang Im Lee, Duck Jong Han, Jae Y Ro
1Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. jaero@amc.seoul.kr
2Department of Pathology, Chungbuk National University College of Medicine, Cheongju, Korea.
3Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-736, Korea.
ABSTRACT
Mixed ductal-endocrine carcinoma of the pancreas is composed of ductal and endocrine carcinoma components and each component makes up a significant proportion in the primary tumor as well as in the tumor of metastatic sites. Mixed ductal-endocrine pancreatic carcinoma is exceptionally rare and, to our knowledge, only five cases have been reported in the literature. Recently we experienced a case of mixed ductal-endocrine pancreatic carcinoma with regional lymph node and hepatic metastases in a 63-year-old woman. Here, we report a case of mixed ductal-endocrine pancreatic carcinoma with a review of the literature.
Key Words: Neoplasms; Complex and Mixed-Pancreas-Carcinoma; Ductal-Endocrine Gland Neoplasm-Immunohistochemistry