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The Korean Journal of Pathology 2005;39(4): 269-272.
Giant Cell Tumor with an Unusual Cartilage Matrix: A Case Report.
Ingu Do, Kyung Nam Ryu, Chung Soo Han, Yong Koo Park
1Department of Pathology, College of Medicine, Kyung Hee University, Seoul, Korea. ykpark@khmc.or.kr
2Departments of Radiology, Kyung Hee University Hospital, Seoul 130-702, Korea. ykpark@khmc.or.kr
3Departments of Orthopedic Surgery, Kyung Hee University Hospital, Seoul 130-702, Korea.
Giant cell tumor of bone is a locally aggressive benign neoplasm, which is composed of oval or plump, spindle-shaped mononuclear cells and uniformly distributed multinucleated giant cells. Bone or cartilage matrix production by the tumor cells is usually not seen. We present a pathologically proven case of giant cell tumor, arising in the acetabulum and pubic bone, with unusual cartilage matrix production. We also discuss the differential diagnosis from a chondroblastoma as well as a giant cell-rich osteosarcoma.
Key Words: Giant cell tumor, Cartilage