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The Korean Journal of Pathology 2006;40(2): 148-150.
Inflammatory Myofibroblastic Tumor of the Stomach: A Case Report.
Joon Mee Kim, In Suh Park, Lucia Kim, Suk Jin Choi, Jee young Han, Young Chae Chu, Kyoung Rae Kim
1Department of Pathology, Inha University College of Medicine, Inchon, Korea. jmkpath@inha.ac.kr
2Department of Surgery, Inha University College of Medicine, Inchon, Korea.
3Inha Research Institute for Medical Science, Inchon, Korea.
ABSTRACT
Inflammatory myofibroblastic tumor of the stomach is a rare tumor-like, benign disease with an uncertain pathogenesis. A 15-year-old male presented with epigastric pain. Endoscopic ultrasonography revealed a 2.3 cm sized ovoid intramuscular mass in the lower body of the stomach at the lesser curvature. Histologically, the tumor was composed of smooth muscle actin positive- and vimentin positive spindle cells and there were a large number of lymphocytes, plasma cells and histiocytes in the fibrotic background. The spindle cells were also positive for ALK1, but negative for EBV in situ hybridization.
Key Words: Inflammatory myofibroblastic tumor; Inflammatory pseudotumor; ALK; Stomach