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The Korean Journal of Cytopathology 1998;9(2): 147-154.
Cytologic Analysis of Adenocarcinoma of the Cervicovaginal Smears .
Jung Yeon Kim, Hye Jae Cho, Kyung Ja Cho, Hong Kyoon Lee
Department of Diagnostic Pathology, Sanggye Paik Hospital, College of Medicine, Inje University.
We have investigated the cervicovaginal smears in order to define the cytologic features of uterine adenocarcinomas. Total 22 cases were reviewed(12 cases from the Sanggye Paik hospital, Inje university and 10 cases from the Korea Cancer Center Hospital) from January 1992 to December 1997. Five cases were endometrial adenocarcinomas and the remaining 17 cases were cervical adenocarcinomas. Se venteen cases of cervical adenocarcinomas were divided into endometrioid(6 cases), endocervical(7 cases), mixed endometrioid and endocervical(1 case), papillary (2 cases), and adenosquamous(1 case) carcinomas. The background of endocervical adenocarcinoma was hemorrhagic or inflammatory. The tumor diathesis was less prominent than that of the squamous cell carcinoma. The prominent features of the endocervical type adenocarcinomas were large and loose clusters, large intra cytoplasmic vacuoles, and prominent overlapping and peripheral palisading of nuclei. In contrast, the endometrioid adenocarcinomas showed small and compact clusters, and small intracytoplasmic vacuoles. The detection rate of endometrial adeno carcinoma was lower than that of the endocervical adenocarcinoma.
Key Words: Cervicovaginal smear; Adenocarincoma; Endometrioid; Endocervical; Cytology