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The Korean Journal of Pathology 2006;40(6): 469-471.
Polycystic Kidney Disease Presenting as Subarachnoid Hemorrhage Due to Ruptured Cerebral Aneurysm: An Autopsy Case.
Yoo Duk Choi, Han Young Lee, Youn Shin Kim
Department of Forensic Medicine, Western District Office, National Institute of Scientific Investigation, Jeollanamdo, Korea. ysk007fm@hotmail.com
Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disorder characterized by multiple expanding cysts in both kidneys, and they ultimately destroy the renal parenchyma and cause renal failure. Intracranial aneurysms are found in approximately 10% to 15% of ADPKD patients. Subarachnoid hemorrhage (SAH) from a ruptured intracranial aneurysm is a frequent complication in patients with ADPKD and it makes up a considerable proportion of the causes of death in this group of patients. We report here an autopsy case of polycystic kidney disease that was morphologically identical to ADPKD, and the patients had presented after death with SAH due to a ruptured cerebral aneurysm.
Key Words: Polycystic kidney disease; Cerebral aneurysm; Subarachnoid hemorrhage
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