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The Korean Journal of Pathology 2007;41(6): 420-423.
Borderline Clear Cell Adenofibromatous Tumors of the Ovary: Two Case Reports.
Heejeong Lee, Tae Jung Kim, Jeana Kim, Eun Joo Seo, Kyo Young Lee
Department of Hospital Pathology, The Catholic University of Korea, Seoul, Korea. ejseo@catholic.ac.kr
Borderline clear cell adenofibromatous tumors are rare with only 26 cases reported in the English literature. Five of these cases exhibited microinvasion and 4 demonstrated intraepithelial carcinoma. We report 2 cases, one typical case and the other with microinvasion. The histological findings revealed widely spaced and focally crowded, variably-sized atypical glands or tubules lined by clear, eosinophilic or hobnail cells set in a dense fibrous stroma. One of the two cases had small solid nests or single cells in the stroma around the proliferative glands less than 1 mm in length that was considered to be a microinvasion.
Key Words: Ovary; Borderline; Clear cell; Microinvasion