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The Korean Journal of Pathology 2008;42(2): 118-122.
Chronic Sclerosing Dacryoadenitis: Report of 2 Cases.
Ji Eun Kwon, Sang Kyum Kim, Sang Ryul Lee, Woo Ick Yang, Haeryoung Kim
1Department of Pathology and Brain Korea 21 Project for Medical Science, Korea.
2Department of Ophthalmology, Yonsei University Health System, Seoul, Korea.
3Department of Pathology, Seoul National University Bundang Hospital, Seongnam, Korea. hkim759@snubh.org
Chronic sclerosing dacryoadenitis is a rare and under-recognized chronic inflammatory disease of the lacrimal gland. We describe 2 patients with a localized type of chronic sclerosing dacryoadenitis. Both patients presented with a slowly growing painless mass of the eyelid mimicking a tumorous lesion. The morphologic findings of the masses excised under the clinical diagnosis of lymphoma closely recapitulate those of chronic sclerosing sialadenitis (Kuttner tumor). Immunohistochemical staining demonstrated an increased population of IgG4-positive plasma cells confirming that this disease also belongs to the spectrum of a recently described IgG4-related sclerosing disease.
Key Words: Dacryocystitis; Lacrimal apparatus