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Massive Perivillous Fibrin Deposition in Placenta.
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HOME > J Pathol Transl Med > Volume 42(4); 2008 > Article
Case Report Massive Perivillous Fibrin Deposition in Placenta.
Dae Woon Eom, Gil Hyun Kang, Chung Hyun Cho, Sang Wook Yi, Han Moie Park, Sang Su Lee, U Seog Son
Journal of Pathology and Translational Medicine 2008;42(4):236-239
DOI: https://doi.org/
1Department of Pathology, University of Ulsan College of Medicine, Gangneung, Korea. edwjyh@gnah.co.kr
2Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Gangneung, Korea.
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Massive perivillous fibrin deposition (MFD) is a rare condition characterized by heavy accumulation of fibrin in intervillous or perivillous spaces encasing villi throughout the placenta. This condition may cause varying degrees of placental insufficiency, leading to a significantly increased risk of intrauterine growth retardation, intrauterine death, and pre-term delivery. However, the objective criteria for the diagnosis of MFD have not been clearly established. We report a case of MFD associated with intrauterine growth retardation and preterm premature rupture of membranes.

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