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The Korean Journal of Pathology 2009;43(2): 182-184.
doi: https://doi.org/10.4132/KoreanJPathol.2009.43.2.182
Giant Cell Tumor-like Proliferation Associated with Renal Staghorn Calculi: A Case Report.
Han Seong Kim, Mee Joo, Sun Hee Chang, Ji Eun Kwak, Sang Hwa Shim, Sung Yong Cho
1Department of Pathology, College of Medicine, Inje University, Goyang, Korea. hskim@paik.ac.kr
2Department of Urology, College of Medicine, Inje University, Goyang, Korea.
A 62-year-old man with left flank pain and hematuria was shown to have a staghorn stone in left renal pelvis. Grossly, renal pelvis and calyces were markedly dilated with cystic and hemorrhagic degeneration and renal parenchyma was atrophied. A tumor-like mass was located in a hemorrhagic cyst of the renal upper pole. This mass consisted of giant cells and stromal cells mimicking a giant cell tumor of bone. This giant cell tumor-like proliferation may represent a response to hemorrhage into a cystic cavity. Recognition of this finding is important to avoid the over-diagnosis of neoplastic lesions.
Key Words: Kidney; Giant cell tumors; Cell proliferation; Calculi