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The Korean Journal of Pathology 2009;43(3): 263-265.
doi: https://doi.org/10.4132/KoreanJPathol.2009.43.3.263
Intranodal Palisaded Myofibroblastoma with Desmin Expression : A Brief Case Report.
Dong Chul Kim, Tae Hoon Kang, Min A Kim, Yoon Kyung Jeon
1Department of Pathology, Seoul National University Hospital, Seoul, Korea.
2Department of Pathology, GyeongSang National University Hospital, Jinju, Korea. kdcjes@hanmail.net
Intranodal palisaded myofibroblastoma is a rare benign mesenchymal neoplasm of the lymph node. It is characterized by intranodal spindle cell proliferation along with amianthoid fibers and prominent hemorrhage. It has been rarely reported in South Korea. We report here on a case of palisaded myofibroblastoma that arose in the left inguinal lymph node. The tumor mass was well demarcated, and it was composed of a proliferation of benign-looking spindle cells. It showed focal hemorrhage and a fibrous pseudocapsule. The tumor cells displayed little pleomorphism, no mitotic count, and characteristic palisading nuclei and amianthoid fibers. The tumor cells were positive for smooth muscle actin, vimentin, and also for desmin, but they were negative for S-100 protein, supporting the diagnosis of myofibroblastoma.
Key Words: Lymph node; Mesenchyme; Myofibroblastoma