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- Case Report The Cytologic Features of Desmoplastic Small Round Cell Tumor with Intranuclear Inclusions : A Case Report .
- Ho Chang Lee, Hye Suk Han, Ok Jun Lee
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Journal of Pathology and Translational Medicine 2009;43(3):279-284
DOI: https://doi.org/10.4132/KoreanJPathol.2009.43.3.279
1Department of Pathology, Chungbuk National University College of Medicine, Cheongju, Korea. ojlee@chungbuk.ac.kr
2Department of Internal Medicine, Chungbuk National University College of Medicine, Cheongju, Korea.
2Department of Internal Medicine, Chungbuk National University College of Medicine, Cheongju, Korea.
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Abstract
Desmoplastic small round cell tumor (DSRCT) is a rare neoplasm of young adults and it is characterized by polyphenotypic differentiation. We experienced a case of abdominal DSRCT that occurred in a 19-year-old female who presented with painful swelling of her right forearm. The tumor was cytokeratin-negative and it exhibited some tumor cells with intranuclear inclusions. Molecular demonstration of EWS-WT1 fusion transcripts is particularly useful to confirm the diagnosis of DSRCT without epithelial differentiation. We report here on a case of cytokeratin-negative DSRCT that showed an unusual feature of intranuclear inclusions.
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