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The Korean Journal of Pathology 2009;43(4): 382-385.
doi: https://doi.org/10.4132/KoreanJPathol.2009.43.4.382
Cytologic Diagnosis of Malignant Pleural Effusion in Multiple Myeloma: Two Case Reports.
Yoo Duk Choi, Sung Sun Kim, Chang Woo Han, Ji Shin Lee, Jong Hee Nam, Sang Woo Juhng, Chan Choi
1Department of Pathology, Chonnam National University Medical School, Gwangju, Korea. cchoi@chonnam.ac.kr
2Brain Korea 21 Project, Center for Biomedical Human Resources at Chonnam National University, Gwangju, Korea.
Malignant pleural effusion in multiple myeloma (MM) is extremely rare and is associated with poor prognosis. We experienced two cases of MM IgA type with malignant pleural effusion. The diagnoses were based on characteristic cytology and CD138 immunocytochemistry. The patients received several cycles of combination chemotherapy, since symptoms were more aggressive with an uncontrolled pleural effusion. We review the clinical features of these cases and literature concerning myelomatous pleural effusion.
Key Words: Cytology; Malignant pleural effusion; Multiple Myeloma