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HOME > J Pathol Transl Med > Volume 44(3); 2010 > Article
Case Report Malignant Fibrous Histiocytoma Arising in a Mature Cystic Teratoma of the Ovary: A Case Report.
Soyoung Im, Sun Mi Lee, Ji Han Jung, Hyun Joo Choi, Jinyoung Yoo, Seok Jin Kang, Kyo Young Lee
Journal of Pathology and Translational Medicine 2010;44(3):322-325
DOI: https://doi.org/10.4132/KoreanJPathol.2010.44.3.322
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Department of Pathology, The Catholic University of Korea College of Medicine, Seoul, Korea. jinyyoo@catholic.ac.kr

A 50-year-old female patient presented with anorexia and weight loss. Pelvic computed tomography revealed a 12.5 x 7.3 cm heterogeneous mass in the left ovary. About 30% of the tumor was occupied by a mature cystic teratoma. The remaining solid portion was composed of fibrous and histiocytic elements, arranged in storiform patterns admixed with bizarre giant cells. The mitotic index was 8 per 10 high power fields, including atypical mitoses. The only immunopositivity was for vimentin. The tumor was diagnosed as a malignant fibrous histiocytoma arising in a mature cystic teratoma. To the best of our knowledge, this is only the third such case in the English language literature.

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