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The Korean Journal of Cytopathology 2002;13(1): 38-41.
Ureteral Washing Cytology of Localized Ureteral Amyloidosis: A Case Report.
Won Ae Lee, Jeong Hae Kie, Yoon Mi Jeen, Mi Kyung Lee
Department of Pathology, National Health Insurance Corporation Ilsan Hospital, Koyang, Korea. spath@nhimc.or.kr
Localized amyloidosis of the ureter is rare and clinically confused with neoplasm. We describe a case of localized amyloidosis of the ureter in which the presence of amyloid was detected in ureteral washing cytology. A 75-year-old female presented with gross hematuria. Abdominal CT and retrograde pyelography revealed hydronephrosis and hydroureter on the left side with abrupt narrowing of the distal ureter. Ureteral washing cytology yielded a hypocellular smear with many irregular clumps of amorphous, extracellar, waxy material. Biopsy sections demonstrated submucosal deposits of eosinophilic amorphous material which gave characteristic apple green birefringence with Congo-red stain under the polarized light. Familarity with the cytologic features of amyloid is helpful for preoperative diagnosis and proper treatment.
Key Words: Amyloidosis; Ureter; Washing cytology