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The Korean Journal of Pathology 1985;19(1): 88-91.
Malignant Acanthosis Nigricans Associated with Stomach Adenocarcinoma.
Young Hee Jee, Eun Joo Seo, Mi Kyung Hur, Chin Hee Cho, Sun Moo Kim
Department of Clinical Pathology, Medical College, Seoul, Korea.
Malignant acanthosis nigricans is very rare disease. The disease is related with internal malignancy, especially gastrointestinal tract malignancy. Reported occurrence rate of malignant acanthosis nigricans associated internal malignancies are 64% of stomach adenocarcinoma, 27% of other organs of abdomen (liver, gall bladder, small intestine, rectum, uterus, ovary), 9% of non-abdominal organs(breast, lung). We report a case of malignant acanthosis nigricans associated with stomach adenocarcinoma from 20-year-old female and discuss review of literature on a acanthosis nigricans briefly.