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The Korean Journal of Pathology 1986;20(3): 332-335.
Aspiration Biopsy Cytology of Malignant Fibrous Histiocytoma.
Moon Hyang Park, Eun Kyung Hong, Jung Dal Lee
Department of Pathology, College of Medicine, Han Yang University, Seoul, Korea.
Cytologic findings of malignant cells obtained by fine needle aspiration from a huge retroperitoneal malignant fibrous histiocytoma were described. The smears contained numerous malignant cells, isolated or in clusters, in a bloody background. The malignant cells had abundant pleomorphic foamy or acidophilic cytoplasm with occasional multilobated vesicular nuclei and prominent nucleoli. Dual differentiation, both histiocytic and fibroblastic types, and neutrophilic inflammatory background were diagnostic of this neoplasm. The report indicated that study of aspiration cytology specimen from a soft tissue tumor was a valuable adjunct to histologic examination.