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The Korean Journal of Pathology 1991;25(3): 263-268.
Pulmonary Alveolar Proteinosis: A case report.
Chang Ho Cho, Yoon Kyung Sohn, Jyung Sik Kwak, Jung Yoon Choi, Won Sik Lee, Tae Hoon Jung
1Department of Pathology, School of Medicine, Kyungpook National University, Taegu, Korea.
2Department of Internal Medicine, School of Medicine, Kyungpook National University, Taegu, Korea.
A case of pulmonary alveolar proteinosis is reported. Most of the alveolar spaces were filled with amorphous deep eosinohilic material which revealed strong positive reaction to periodic acid-Schiff staining. Electron microscopic observation of this material showed numerous lamellar bodies in the alveolar spaces and cytoplasms of alveolar macrophages. A part of them were concentric multilamellated type A lamellar bodies and the other were finger printlike type B bodies. Combined type A and type B lamellar bodies were rarely present. From the above features it is suggested that both type A and B lamellar bodies could be transformed one another and those lamellar bodies may be originated from pulmonary surfactant.
Key Words: Pulmonary alveolar proteinosis; Lamellar body
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