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HOME > J Pathol Transl Med > Volume 26(1); 1992 > Article
Original Article Epithelial-Myoepithelial Carcinoma of Intercalated Duct of Parotid Gland.
Soong Deok Lee, Doo Hyun Chung, Sung Hye Park, Chul Woo Kim, Je G Chi
Journal of Pathology and Translational Medicine 1992;26(1):76-81
DOI: https://doi.org/
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Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.

Epithelial-myoepithelial carcinoma of intercalated duct(origin) is a recently described tumor characterized by its typical biphasic pattern of central duct like cell and peripheral clear cell. We described a case of epithelial-myoepithelial carcinoma in a 10-year-old boy. Microscopically, the tumor showed typical biphasic pattern, diffuse proliferation of clear cells and linining epithelial cells of tubular structures. Immunohistochemically, the clear cell showed positive reaction to S-100 protein, and the epithelial cells expressed cytokeratin indicating myoepithelial and epithelial differentiation respectively. Biphasic differentiation of the tumor cells could be also proved by electronmicroscopic study.

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