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Byoung Kwon Kim 1 Article
Large Cell Calcifying Sertoli Cell Tumor of the Testis: A Case Study and Review of the Literature
Dae Hyun Song, Seong Muk Jeong, Jong Tak Park, Gak Won Yun, Byoung Kwon Kim, Jong Sil Lee
Korean J Pathol. 2014;48(1):50-53.   Published online February 25, 2014
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AbstractAbstract PDF

A 24-year-old man was admitted due to an incidentally detected mass in his left testis, which showed radiopaque calcification on plain X-ray film. Left orchiectomy was performed, and the resected testis contained a well-demarcated, hard mass measuring 1.1 cm. Histological analysis revealed that the tumor was composed of neoplastic cells, fibrotic stroma, and laminated or irregularly shaped calcific bodies. The individual cells had abundant eosinophilic or clear cytoplasm with round nuclei, each of which contained one or two conspicuous nucleoli. They were arranged in cords, trabeculae, clusters, and diffuse sheets. There were several foci of intra-tubular growth patterns, with thickening of the basal lamina. Immunohistochemically, the neoplastic cells were positive for S-100 protein and vimentin, focally positive for inhibin alpha, and negative for cytokeratin, CD10, and Melan-A. In addition to reporting this rare case, we also review the relevant literature regarding large cell calcifying Sertoli cell tumors.


Citations to this article as recorded by  
  • Large Cell Calcifying Sertoli Cell Tumor
    Khaleel I. Al-Obaidy, Muhammad T. Idrees, Eman Abdulfatah, Lakshmi P. Kunju, Angela Wu, Thomas M. Ulbright
    American Journal of Surgical Pathology.2022; 46(5): 688.     CrossRef
  • Intratubular large cell hyalinizing Sertoli cell tumor of the testis presenting with prepubertal gynecomastia: a case report
    Hale Tuhan, Ayhan Abaci, Banu Sarsık, Tülay Öztürk, Mustafa Olguner, Gonul Catli, Ahmet Anik, Nur Olgun, Ece Bober
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    Sarah Scollon, Amanda Knoth Anglin, Martha Thomas, Joyce T. Turner, Kami Wolfe Schneider
    Journal of Genetic Counseling.2017; 26(3): 387.     CrossRef
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    Juan A. Siordia
    Journal of Cardiac Surgery.2015; 30(7): 560.     CrossRef

JPTM : Journal of Pathology and Translational Medicine