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Hyo Jeong An 1 Article
Sebaceous Carcinoma Arising in Mature Cystic Teratoma of Ovary
Hyo Jeong An, Yong Han Jung, Hye Kyoung Yoon, Soo Jin Jung
Korean J Pathol. 2013;47(4):383-387.   Published online August 26, 2013
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  • 9 Citations
AbstractAbstract PDF

Roughly 1% of mature cystic teratomas undergo malignant transformation. In particular, cutaneous-type adnexal neoplasms may occur in mature cystic teratomas. Sebaceous carcinomas, which arise from mature cystic teratomas, have rarely been observed, with only seven cases previously reported. Here, we present a case of a 69-year-old female who had pelvic pain for two weeks and who subsequently underwent bilateral salpingo-oophorectomy and hysterectomy. Her left ovary showed a unilocular cyst, measuring 22.0 cm in diameter, filled with sebaceous material and a few hairs. A luminally-protruding solid mass measuring 4.0 cm in diameter was also noted. Microscopic findings revealed lobular or diffusely arranged basophilic, atypical sebaceous cells connected to a typical mature cystic teratoma. Tumor cells demonstrated positive immunoreactivity for high molecular weight cytokeratin, cytokeratin 7, cytokeratin 19, epithelial membrane antigen, and carcinoembryonic antigen. Here, we present a case of sebaceous carcinoma arising from a mature cystic teratoma along with a review of previously published reports.


Citations to this article as recorded by  
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  • Malignant transformation of an ovary mature cystic teratoma: case report and review of the literature
    Elkin Fabián Dorado-Roncancio, Oscar Joel Carrillo-Garibaldi
    Obstetrics & Gynecology International Journal.2019;[Epub]     CrossRef
  • A case of ovarian clear cell carcinoma arising from ovarian mature cystic teratoma
    Kazuya Maeda, Yoshito Terai, Shinichi Terada, Hiroshi Maruoka, Yuhei Kogata, Keisuke Ashihara, Yoshimichi Tanaka, Tomohito Tanaka, Hiroshi Sasaki, Satoshi Tsunetoh, Takashi Yamada, Masahide Ohmichi
    Journal of Ovarian Research.2018;[Epub]     CrossRef
  • Sebaceous carcinoma arising within an ovarian mature cystic teratoma: A case report with discussion of clinical management and genetic evaluation
    Alyssa Wield, Melissa Hodeib, Mohammad Khan, Lindsay Gubernick, Andrew J. Li, Shivani Kandukuri
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JPTM : Journal of Pathology and Translational Medicine