- Metallic implant-associated lymphoma: ALK-negative anaplastic large cell lymphoma associated with total knee replacement arthroplasty
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Jai-Hyang Go
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J Pathol Transl Med. 2023;57(1):75-78. Published online January 10, 2023
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DOI: https://doi.org/10.4132/jptm.2022.10.30
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Abstract
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- Metallic implant-associated lymphomas are extremely rare. Only seven cases have been reported in association with knee joint arthroplasty, and all tumors were large B-cell lymphomas. This report is the first case of anaplastic large cell lymphoma occurring after total knee replacement arthroplasty. An 80‑year‑old female patient was admitted because of right knee pain for 2 years. She had undergone total knee replacement arthroplasty 10 years prior. Computed tomography showed an irregular osteolytic lesion in the right lateral femoral condyle, adjacent to the metallic prosthesis. Histologic findings reveal sheets of anaplastic tumor cells that were positive for CD2, CD4, CD5, CD43, and CD30 but negative for CD3, CD20, CD15, and anaplastic lymphoma kinase. Epstein-Barr encoding region in situ hybridization was negative. Analysis of T-cell receptor γ gene rearrangement studies using BIOMED-2–based multiplex polymerase chain reaction confirmed monoclonal T cell proliferation. The woman was finally diagnosed with ALK-negative anaplastic large cell lymphoma.
- Follicular T-Cell Lymphoma with Concomitant Lennert Lymphoma
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Seungkyu Choi, Jai-Hyang Go
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J Pathol Transl Med. 2018;52(6):425-427. Published online July 16, 2018
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DOI: https://doi.org/10.4132/jptm.2018.04.16
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- T-cell lymphoma with a granulomatous lesion of the lungs after autologous hematopoietic stem cell transplantation for Epstein–Barr virus-positive diffuse large B-cell lymphoma: a unique rare case of metachronous B-cell and T-cell lymphoma
Yusuke Kajimoto, Yasuhiro Terasaki, Mika Terasaki, Shinobu Kunugi, Yugo Okabe, Satoshi Wakita, Koiti Inokuchi, Akira Shimizu Diagnostic Pathology.2020;[Epub] CrossRef
- Aberrant CD3 Expression in a Relapsed Plasma Cell Neoplasm
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Jai-Hyang Go
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J Pathol Transl Med. 2018;52(3):202-205. Published online December 21, 2017
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DOI: https://doi.org/10.4132/jptm.2017.09.05
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