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Ning Geng 1 Article
Ghost Cell Odontogenic Carcinoma Arising from Calcifying Cystic Odontogenic Tumor: A Case Report
Zhi-Yu Zhu, Zhi-Gang Chu, Yu Chen, Wei-Ping Zhang, Di Lv, Ning Geng, Ming-Zhong Yang
Korean J Pathol. 2012;46(5):478-482.   Published online October 25, 2012
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AbstractAbstract PDF

Ghost cell odontogenic carcinoma (GCOC) is an exceptionally rare and malignant odontogenic tumor with aggressive growth characteristics. We describe a case of GCOC which was considerably derived from a previously resected calcifying cystic odontogenic tumor (CCOT). Cellular atypia, mitotic activity, Ki-67 labeling index and matrix metalloprotease-9 positive expression rate were all increased in the currently resected specimen compared to the initial one. This is a rare case of malignant transformation of CCOT to GCOC with respect to its histopathological and immunohistochemical findings.


Citations to this article as recorded by  
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    Medical Molecular Morphology.2022; 55(1): 76.     CrossRef
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    Gustavo de Souza Vieira, Pâmella de Pinho Montovani, Rafaela Elvira Rozza-de-Menezes, Karin Soares Gonçalves Cunha, Danielle Castex Conde
    Head and Neck Pathology.2021; 15(4): 1265.     CrossRef
  • Ghost cell odontogenic carcinoma of the jaws: Report of two cases and a literature review
    Meng-Qi Jia, Jun Jia, Li Wang, Hai-Xiao Zou
    World Journal of Clinical Cases.2019; 7(3): 357.     CrossRef
  • Ghost cell odontogenic carcinoma with suspected cholesterol granuloma of the maxillary sinus in a patient treated with combined modality therapy
    You Qin, Yanwei Lu, Liduan Zheng, Hong Liu
    Medicine.2018; 97(7): e9816.     CrossRef
  • A lesion categorized between ghost cell odontogenic carcinoma and dentinogenic ghost cell tumor with CTNNB1 mutation
    Yae Ohata, Kou Kayamori, Akane Yukimori, Kanako Sumikura, Toshimitsu Ohsako, Hiroyuki Harada, Kei Sakamoto, Tohru Ikeda
    Pathology International.2018; 68(5): 307.     CrossRef
  • A case of large ghost cell odontogenic carcinoma arising in the mandible
    Daisuke ARAKI, Shunichi YOSHIDA, Keisuke KOYAMA, Shuutarou ISHII, Toshihiro HASEGAWA, Sadao OOYAMA
    Japanese Journal of Oral and Maxillofacial Surgery.2018; 64(12): 708.     CrossRef
  • Three-dimensional volumetric analysis of ghost cell odontogenic carcinoma using 3-D reconstruction software: a case report
    João Pedro Perez Gomes, Andre Luiz Ferreira Costa, Carlos Takahiro Chone, Albina Messias de Almeida Milani Altemani, João Maurício Carrasco Altemani, Carmen Silvia Passos Lima
    Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology.2017; 123(5): e170.     CrossRef
  • Ghost cell odontogenic carcinoma transformed from dentinogenic ghost cell tumor of the maxilla after recurrences
    Sase Miwako, Itoh Hiroto, Nakano Takahumi, Hayasaka Junichi, Noguchi Tadahide, Jinbu Yoshinori, Mori Yoshiyuki
    Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology.2017; 29(5): 438.     CrossRef
  • Ki-67 and p53 expression in ghost cell odontogenic carcinoma: a case report and literature review
    G. Del Corso, M. L. Tardio, D. B. Gissi, C. Marchetti, L. Montebugnoli, A. Tarsitano
    Oral and Maxillofacial Surgery.2015; 19(1): 85.     CrossRef
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    Pinaki Bose, Erin D. Pleasance, Martin Jones, Yaoqing Shen, Carolyn Ch’ng, Caralyn Reisle, Jacqueline E. Schein, Andrew J. Mungall, Richard Moore, Yussanne Ma, Brandon S. Sheffield, Thomas Thomson, Steven Rasmussen, Tony Ng, Stephen Yip, Christopher W. Le
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    Safia K. Ahmed, Masayo Watanabe, Daphne E. deMello, Thomas B. Daniels
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  • Predictive Factors of Potential Malignant Transformation in Recurrent Calcifying Cystic Odontogenic Tumor: Review of the Literature
    Sepideh Mokhtari, Zhaleh Mohsenifar, Maedeh Ghorbanpour
    Case Reports in Pathology.2013; 2013: 1.     CrossRef

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