- Cytopathologic Features of Secretory Carcinoma of Salivary Gland: Report of Two Cases
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Young Ah Kim, Jae Won Joung, Sun-Jae Lee, Hoon-Kyu Oh, Chang Ho Cho, Woo Jung Sung
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J Pathol Transl Med. 2019;53(1):70-74. Published online December 28, 2018
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DOI: https://doi.org/10.4132/jptm.2018.11.09
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- Secretory carcinoma of the salivary gland (SC) is a newly introduced rare salivary gland tumor that shares histological, immunohistochemical, and genetic characteristics with secretory carcinoma of the breast. Here, we report the cytologic features of two cases of SC confirmed by surgical resection. In these two cases, SC was incidentally detected in a 64-year-old female and a 56-yearold male. Fine needle aspiration cytology revealed nests of tumor cells with a papillary or glandular structure floating in mucinous secretions. The tumor cells demonstrated uniform, round, smooth nuclear contours and distinct nucleoli. Multiple characteristic cytoplasmic vacuoles were revealed. Singly scattered tumor cells frequently showed variable sized cytoplasmic vacuoles. The cytopathologic diagnosis of SC should be considered when characteristic cytological findings are revealed. Further immunohistochemistry and gene analyses are helpful to diagnose SC.
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- Salivary Gland Secretory Carcinoma; Review of 13 Years World‐Wide Experience and Meta‐Analysis
Eyal Yosefof, Tomer Boldes, Daniel Dan, Eyal Robenshtok, Yulia Strenov, Gideon Bachar, Thomas Shpitzer, Aviram Mizrachi The Laryngoscope.2024; 134(4): 1716. CrossRef - Efficacy of Fine-Needle Aspiration Cytology in Diagnosing Secretory Carcinoma of Salivary Gland: A Systematic Review and Meta-Analysis
Pooja Sharma Kala, Mamta Gupta, Naveen Thapliyal Acta Cytologica.2024; 68(2): 83. CrossRef - An Underappreciated Cytomorphological Feature of Secretory Carcinoma of Salivary Gland on Fine Needle Aspiration Biopsy: Case Report with Literature Review
Yinan Hua, Bing Leng, Kenneth E. Youens, Lina Liu Head and Neck Pathology.2022; 16(2): 567. CrossRef - Prognostic factors in mammary analogue secretory carcinomas of the parotid gland: Systematic review and meta‐analysis
Stefan Janik, Muhammad Faisal, Blazen Marijić, Stefan Grasl, Matthaeus Ch. Grasl, Gregor Heiduschka, Boban M. Erovic Head & Neck.2022; 44(3): 792. CrossRef - A systematic review of secretory carcinoma of the salivary gland: where are we?
Lísia Daltro Borges Alves, Andreia Cristina de Melo, Thayana Alves Farinha, Luiz Henrique de Lima Araujo, Leandro de Souza Thiago, Fernando Luiz Dias, Héliton Spíndola Antunes, Ana Lucia Amaral Eisenberg, Luiz Claudio Santos Thuler, Daniel Cohen Goldember Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology.2021; 132(4): e143. CrossRef - Clinical characteristics of acinic cell carcinoma and secretory carcinoma of the parotid gland
Tetsuya Terada, Ryo Kawata, Keiki Noro, Masaaki Higashino, Shuji Nishikawa, Shin-ichi Haginomori, Yoshitaka Kurisu, Hiroko Kuwabara, Yoshinobu Hirose European Archives of Oto-Rhino-Laryngology.2019; 276(12): 3461. CrossRef
- Pleomorphic Adenoma of the Trachea: A Case Report
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Ki-Sung Park, Woo Jung Sung
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Korean J Pathol. 2013;47(4):399-401. Published online August 26, 2013
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DOI: https://doi.org/10.4132/KoreanJPathol.2013.47.4.399
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8,435
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- Unexpected cause of dyspnea: A case of pleomorphic adenoma in the trachea
Kaoutar Maslouhi, Eric Michel Charlemagne Kessi, Safae Lanjeri, Kaouthar Sfar, Salma Malak Ridah, Youssef Omor, Rachida Latib, Sanae Amalik Radiology Case Reports.2025; 20(2): 1229. CrossRef - Pleomorphic adenoma of the trachea: A case report
Mayu Inomata, Shoei Kuroki, Nobuyuki Oguri, Yuichiro Sato, Fumiya Kawano, Ryo Maeda International Journal of Surgery Case Reports.2023; 109: 108499. CrossRef - Corrélation clinique, endoscopique, histologique et radiologique des tumeurs et pseudo-tumeurs de la trachée
Y. El Hassani, L. Belliraj, A. Miry, M. Haloua, N. Hammas, Y. Ouadnouni, M.Y. Alaoui Lamrani, M. Boubbou, H. El Fatemi, M. Serraj, M. Smahi, B. Amara, M. Maaroufi, B. Alami Journal d'imagerie diagnostique et interventionnelle.2021; 4(5): 317. CrossRef - Pleomorphic Adenoma of the Trachea
Abel P. David, Stephen R. Bakos, James J. Daniero Ear, Nose & Throat Journal.2020; 99(4): 235. CrossRef - A case report of bronchial pleomorphic adenoma in a child in China
Haiqin Zhong, Silei Yan, Kung Jiang, Yijing Hu, Xiaoyan Dong BMC Pulmonary Medicine.2020;[Epub] CrossRef - Pleomorphic adenoma of the trachea: A case report and review of the literature
Qian-Nuan Liao, Ze-Kui Fang, Shu-Bing Chen, Hui-Zhen Fan, Li-Chang Chen, Xi-Ping Wu, Xi He, Hua-Peng Yu World Journal of Clinical Cases.2020; 8(23): 6021. CrossRef - Pleomorphic adenoma of the trachea: A case report and review of the literature
Qian-Nuan Liao, Ze-Kui Fang, Shu-Bing Chen, Hui-Zhen Fan, Li-Chang Chen, Xi-Ping Wu, Xi He, Hua-Peng Yu World Journal of Clinical Cases.2020; 8(23): 6026. CrossRef - Obstructive tracheal neoplasm
Badreeddine Alami, Saïd Boujraf, Mohamed Smahi, Mounia Serraj, Moulay Youssef Alaoui Lamrani, Meryem Boubbou, Mustapha Maaroufi Formosan Journal of Surgery.2019; 52(3): 92. CrossRef - Tracheal pleomorphic adenoma with coexisting pulmonary tuberculoma
Jehun Kim, Chul-Ho Oak, Tae-Won Jang, Mann-Hong Jung Yeungnam University Journal of Medicine.2018; 35(1): 114. CrossRef - Right main bronchial pleomorphic adenoma
Zhixing Zhu, Xihua Lian, Dongyong Yang Medicine.2018; 97(42): e12648. CrossRef
- Epithelioid Trophoblastic Tumor: Clinicopathologic and Immunohistochemical Analysis of Three Cases
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Woo Jung Sung, Hyeong Chan Shin, Min-Kyung Kim, Mi Jin Kim
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Korean J Pathol. 2013;47(1):67-73. Published online February 25, 2013
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DOI: https://doi.org/10.4132/KoreanJPathol.2013.47.1.67
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10,501
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Epithelioid trophoblastic tumor is an unusual type of trophoblastic tumor. Here we report on the clinicopathologic and immunohistochemical features of three cases of epithelioid trophoblastic tumor. All three patients were of reproductive age and presented with vaginal bleeding and mild elevation of human chorionic gonadotropin (hCG). All patients underwent a hysterectomy. The tumors consisted of epithelioid intermediate trophoblastic cells that were mononucleated and eosinophilic, or showed clear cytoplasm on microscopic examination. One case presented with a focal choriocarcinoma component. Immunohistochemically, the tumors displayed diffuse positivity for cytokeratin 18, E-cadherin, epidermal growth factor receptor, and p53 and focal positivity for p63 and hCG. However, expression of α-inhibin and placental alkaline phosphatase was almost negative. Tests for human placental lactogen and epithelial membrane antigen were also negative in all cases.
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Citations
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- Epithelioid Trophoblastic Tumour: A Case with Genetic Linkage to a Child Born over Seventeen Years Prior, Successfully Treated with Surgery and Pembrolizumab
David Pisani, Jean Calleja-Agius, Riccardo Di Fiore, John J. O’Leary, James P. Beirne, Sharon A. O’Toole, Ana Felix, Ian Said-Huntingford Current Oncology.2021; 28(6): 5346. CrossRef - Epithelioid Trophoblastic Tumor
Stephanie M. McGregor, Larissa V. Furtado, Anthony G. Montag, Rebecca Brooks, Ricardo R. Lastra International Journal of Gynecological Pathology.2020; 39(1): 8. CrossRef - Epithelioid trophoblastic tumor in a postmenopausal woman: A case report and review of the literature in the postmenopausal group
Seyran Yigit, Eylul Gun, Bulent Yilmaz, Zafer Kolsuz Indian Journal of Pathology and Microbiology.2020; 63(5): 98. CrossRef - Double trouble: Extrauterine epithelioid trophoblastic tumor with uterine choriocarcinoma - An autopsy report
Kusum Jashnani, Alshifa Yagana, Niraj Mahajan Indian Journal of Cancer.2020;[Epub] CrossRef - Epithelioid trophoblastic tumor coexisting with choriocarcinoma around an abdominal wall cesarean scar: a case report and review of the literature
Chunfeng Yang, Jianqi Li, Yuanyuan Zhang, Hanzhen Xiong, Xiujie Sheng Journal of Medical Case Reports.2020;[Epub] CrossRef - Placental site trophoblastic tumor and epithelioid trophoblastic tumor: Clinical and pathological features, prognostic variables and treatment strategy
Angiolo Gadducci, Silvestro Carinelli, Maria Elena Guerrieri, Giovanni Damiano Aletti Gynecologic Oncology.2019; 153(3): 684. CrossRef - Diagnosis and Management of Mixed Gestational Trophoblastic Neoplasia: A Study of 16 Cases and a Review of the Literature
Yujia Kong, Guangshi Tao, Liju Zong, Junjun Yang, Xirun Wan, Wenze Wang, Yang Xiang Frontiers in Oncology.2019;[Epub] CrossRef - A Case Series of Five Patients With Pure or Mixed Gestational Epithelioid Trophoblastic Tumors and a Literature Review on Mixed Tumors
Ka Yu Tse, Keith Wan Hang Chiu, Karen Kar Loen Chan, Mandy Man Yee Chu, Siew Fei Ngu, Annie Nga Yin Cheung, Hextan Yuen Sheung Ngan, Philip Pun Ching Ip American Journal of Clinical Pathology.2018; 150(4): 318. CrossRef - MR Imaging of Uterine Epithelioid Trophoblastic Tumor: A Case Report
Sakiko KAGEYAMA, Masafumi KANOTO, Yukio SUGAI, Takeshi SUTO, Satoru NAGASE, Mitsumasa OSAKABE, Takaaki HOSOYA Magnetic Resonance in Medical Sciences.2016; 15(4): 411. CrossRef - Pharmacotherapy of placental site and epithelioid trophoblastic tumours
Fiona Taylor, Barry W Hancock Expert Opinion on Orphan Drugs.2015; 3(1): 75. CrossRef - A Well-Circumscribed Border with Peripheral Doppler Signal in Sonographic Image Distinguishes Epithelioid Trophoblastic Tumor from Other Gestational Trophoblastic Neoplasms
Jiale Qin, Weiwen Ying, Xiaodong Cheng, Xiaodong Wu, Bingjian Lu, Yun Liang, Xinyu Wang, Xiaoyun Wan, Xing Xie, Weiguo Lu, Hai-Yan Lin PLoS ONE.2014; 9(11): e112618. CrossRef
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