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Yunkyung Lee 1 Article
Silent Colonic Malakoplakia in a Living-Donor Kidney Transplant Recipient Diagnosed during Annual Medical Examination
Go Eun Bae, Nara Yoon, Ha Young Park, Sang Yun Ha, Junhun Cho, Yunkyung Lee, Kyoung-Mee Kim, Cheol Keun Park
Korean J Pathol. 2013;47(2):163-166.   Published online April 24, 2013
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AbstractAbstract PDF

Malakoplakia is a characteristic inflammatory condition, which is usually seen in the urogenital tract, and less frequently in the gastrointestinal tract. We present a case of colonic malakoplakia in an immunocompromised patient. A 55-year-old female visited the outpatient clinic for routine cancer surveillance. Her past medical history was significant for kidney transplantation 11 years ago, and she had been taking immunosuppressants. A colonoscopy revealed several depressed flat lesions and elevated polyps, which were 0.3 to 0.4 cm in size and accompanied by whitish exudates. A biopsy revealed an infiltration of histiocytes with ample granular eosinophilic cytoplasm, with some lymphocytes and plasma cells. Many histiocytes had the characteristic morphology, described as Michaelis-Gutmann bodies: one or several round basophilic structures of approximately 1 to 10 µm in size with some being laminated, some appearing homogeneous, and others having a dense central core with a targetoid appearance. These Michaelis-Gutmann bodies were positively stained on von Kossa stain, and were diagnostic for malakoplakia.


Citations to this article as recorded by  
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    Medicina.2023; 59(1): 156.     CrossRef
  • Colonic malakoplakia in a cardiac transplant recipient: A case report
    Sadiya Shafijan
    Indian Journal of Pathology and Microbiology.2020; 63(2): 322.     CrossRef
  • Immunosuppressive drugs and the gastrointestinal tract in renal transplant patients
    Merel M. Tielemans, Gerben A.J. van Boekel, Teun van Gelder, Eric T. Tjwa, Luuk B. Hilbrands
    Transplantation Reviews.2019; 33(2): 55.     CrossRef
  • Malakoplakia of the colon following renal transplantation in a 73 year old woman: report of a case presenting as intestinal perforation
    Andrew Mitchell, Alexandre Dugas
    Diagnostic Pathology.2019;[Epub]     CrossRef
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    Rana Ajabnoor, Mohammad Mawardi, Abdulmonem Almutawa
    Human Pathology: Case Reports.2019; 18: 200323.     CrossRef
  • Malakoplakia after kidney transplantation: Case report and literature review
    John Fredy Nieto-Ríos, Isabel Ramírez, Mónica Zuluaga-Quintero, Lina María Serna-Higuita, Federico Gaviria-Gil, Alejandro Velez-Hoyos
    Transplant Infectious Disease.2017; 19(5): e12731.     CrossRef
  • Megalocytic Interstitial Nephritis Following Acute Pyelonephritis with Escherichia coli Bacteremia: A Case Report
    Hee Jin Kwon, Kwai Han Yoo, In Young Kim, Seulkee Lee, Hye Ryoun Jang, Ghee Young Kwon
    Journal of Korean Medical Science.2015; 30(1): 110.     CrossRef

JPTM : Journal of Pathology and Translational Medicine