Journal of Pathology and Translational Medicine

Volume 11(3); September 1977

Etcs

Histopathologic Study of Chronic Carbon Monoxide Poisoning on the Placenta of the Rat: Kye Yong Song, Eui Keun Ham, Soo Hun Cho*, Dork Ro Yun*; Korean J Cytopathol. 1977;11(3):199-205.

1,099 View
10 Download

Abstract: Carbon monoxide poisoning was the one of the most serious and important problem of public health of Korea because of the use of anthracite coal briquette as the main domestic fuel. There was strong presumtive clinical data that carbon monoxide poisoning during pregnancy can result in major malfomation secondary to apparent hypoxia. In attempting to unravel the mechanism behind the process of abortion, a careful study of the pathologic attention is the placenta would seem in seem in essential part. It was purpose of this report to describe the histologic changes in the placentas of the rats when animals were exposed to carbon monoxide in low concentration and long term during pregnancy. Experimental groups consists of 13 control and 18 pregnant rats. Animals were exposed to 1,000 ppm of carbon monoxide for 60 minutes daily throughout the gestational period. Pathologic changes in the placentas of rats of group of long term exposure of low concentrated carbon monoxide were summarized as follows : 1. In the labyrinth of exposure group were seen marked dilatation of maternal sinuses with vascular congestion and focal sinusoidal rupture, the degree of which were more promenent in the zone of periphery than central area. Sinusoidal walls near the basal zone showed moderate septal thickening as well as diffuse degeneration of trophoblasts such as nuclear swelling, pyknosis and loss of nucleoli. Isalnds of gylcogen cells and multinucleted giant cells were scattered throughout the labyrinth. 2. In the basal zone of exposure group were seen marked cytolysis of glycogen cells and degeneration of giant cells as well as marked vascular congestion and occasional thrombosis of maternal blood channels. Fibrinoid necrosis of decidua was relatively higher in the exposure group than the control rats. 3. In the epithelium of yolk sac was seen considerably intensified vacuolar degeneration in the exposure group than control ones. (This study was supported in part by the research grant (C.M.B. 74-332-5), the China Medical Board of New York)

Primary Ovarian Carcinoid Tumor associated with Cystic Teratoma -A Case Report with Review of the Literature-: Myoung Hee Park, Yong Il Kim, Chung Sook Kim*; Korean J Cytopathol. 1977;11(3):207-215.

1,769 View
10 Download

Abstract: Carcinoid tumors of the ovary are rare, comprising about 0.1 percent of all ovarian neoplasms, and account for less than 1 percent of all carcinoids in the body. Since the first two cases of ovarian carcinoid were described in 1939 by Stewart et a1., both primary and less often metastatic forms have been accumulated in the literature. The most common is primary in the ovary, growing in an insular pattern, typically observed in carcinoids arising in the midgut derivatives ; around 70 cases of this type have been documented in the world literature. Less often ovarian carcinoids of trabecular pattern observed in carcinoids arising in the foregut and the hindgut derivatives have been described. There also have been some reported cases of struma carcinoid of the ovary. Most primary ovarian carcinoids are associated with benign cystic teratomas, but some occur in apparently pure form. To our best knowledge, there has been no single proven case of primary ovarian carcinoid in the Korean literature. Authors are to describe a histochemically and ultra-structurally proven case of a nonfunctioning primary ovarian carcinoid of insular pattern associated with an otherwise classical cystic teratoma in a 44 year-old Korean female patient. Clinical Summary ; A moderately developed and nourished 44 year-old Korean female patient was admitted to the Seoul National University Hospital in July 1974, complaining of dull lower abdominal pain of several months duration. Otherwise she had carried out healthy life. On admission body temperature was 36.8℃, pulse rate 76/min and blood pressure 140/90 mmHg. Auscultation of the chest and heart were normal. Pelvic and rectal examination revealed a double fist sized, doughy and movable right sided intrapelvic mass, and an ovarian cyst was suspected. Routine laboratory finding and chest X-ray film were unremarkable. Urinary 5-hydroxyindoleacetic acid was not determined, and evidence of flushing or diarrhea was not recorded. Operation was performed under the impression of ovarian cyst ; there was a large cystic mass on the site of right ovary but with no adhesion to the surrounding structures. Left ovary was grossly normal. Liver, peritoneal cavity and gastrointestinal tract were free. Hysterectomy and right salpingo-ooph-orectomy were carried out. Hospital course was uneventful and she was discharged at the 8th hospital day, and was lost thereafter for further follow up.

Tuberculosis of Breast -A Case Report-: Yong Heon Kim*, Chung Yoon*, Yong Chul Park*, Hee Kyung Kim, Moon Ho Yang, Chae Koo Lee; Korean J Cytopathol. 1977;11(3):217-222.

1,174 View
10 Download

Abstract: Tuberculosis of the breast, either primary or secondary, is one of the extremely rare disease, compare to the general incidence of the tuberculosis in human beings. However, If we give more attention to the possibility of the mammary tuberculosis, we could detect more cases in. our country because of high prevalence of the tuberculosis. Preoperative clinical diagnosis of the breast tuberculosis is very hard to make because of the difficulties of the differential diagnosis between breast cancer, comedomastitis, and various chronic mastitis which are more common disease in breast. Definite diagnosis of the disease can be done through bacteriologic study and histopathological examination only. Treatment of the disease may be either medical (antituberculous drugs) or surgical. The simple mastectomy or local excision of the lesion is the enough surgical procedure for the disease. For the proper surgical management of all the suspicious breast lesions, we believe the use of the frozen section is essential to avoid unnecessary radical mastectomy. A case of tuberculosis of the breast occurring in a 30-year-old female is presented with summary of the pathological and clinical characteristics, and it’s differential diagnosis is also discussed with review of the literatures. Clinically, she complained of a slightly movable mass of the right breast for 6 years. On operation, ill defined nodular cystic lesions with sinus tract is noted, filled with caseous materials. Complete excision of the nodular mass was performed.

Malignant Mesothelioma of Intrascrotal Tissue: Moon Hyang Park, Hyo Sook Park; Korean J Cytopathol. 1977;11(3):225-229.

1,180 View
10 Download

Abstract: A case designated malignant mesothelioma most probably arising from the tunica vaginalis propria testis is described. The pathological diagnosis was based upon the clinical findings, gross and microscopic morphology, histochemical studies and likeness to the reported examples of mesothelioma arising from pleural and peritoneal mesothelial surfaces. About 5 years before admission the patient underwent orchiectomy under the diagnosis of hydrocele at local clinic with chief complaint of scrotal swelling for 5 years. From 1 year thereafter he noted a small slowly growing mass in the operation site of scrotum. At the time of second operation, 5 years later, a slightly tender, firm, man’s fist sized scrotal mass was excised. The malignant character of the neoplasm was demonstrated by the growing pattern, cytologic alterations and metastasis to the inguinal and pelvice lymph nodes and lungs.

Generalized Cytomegalic Iuclusion Disease -An autopsy case with review of literature-: O.J. Paik, C.C. Cho, S.K. Moon; Korean J Cytopathol. 1977;11(3):231-235.

1,235 View
10 Download

Abstract: An autopsy-verified case of the generalized cytomegalic inclusion disease occurring in a premature male patient was presented, and its clinicopathologic characteristics were discussed with a brief literature review. The lesions were found to be systemic and showed typical cytomegalic inclusion cells having large acidophilic intranuclear and/or intracytoplasmic inclusions in the lungs, liver and kidneys with prominent extramedullary hemopoiesis in the liver, spleen, and kidneys.

A Case of Intracranial Malignant Teratoma: Jong Sang Choi, Joo Hong Yun, Chang Sup Sim, Seung Yong Paik; Korean J Cytopathol. 1977;11(3):237-241.

852 View
10 Download

Abstract: Intracranial teratomas and teratoid tumors are rare, constituting about 0.5% of the total Except germinomas or atypical teratomas, malignant teratomas almost always dysplay some tissue elements which are embriologically immature. Predilection sites of intracranial teratomas are the pineal body, the pituitary region and the posterior fossa in order of frequency. We have reported a case of malignant teratoma experienced in a 16 year-old boy who disclosed occipital headache and dizziness for 3 weeks. The tumor was located at the roof of the third ventricle and resulted in hydrocephalus. Histopathologically, were there variegated structures such as irregular glandular structures which were lined by a single or multiple layers of polygonal or spindle cells. A gland lined by cells having acidophilic secretory material in their cytoplasms and myxoid spindle cells suggesting immature mesenchymal tissue were also encountered.

First
Prev
Page of 1
Next
Last

Previous issues