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What’s new in molecular genetic pathology 2022: immune checkpoint inhibitor biomarkers and select solid tumors
Patricia C. Tsang, Guoli Chen
J Pathol Transl Med. 2022;56(2):113-114.   Published online March 11, 2022
DOI: https://doi.org/10.4132/jptm.2022.01.25
  • 3,155 View
  • 158 Download
  • 1 Web of Science
AbstractAbstract PDF
Predictive biomarker testing plays a critical role in targeted immuno-oncology, including the use of immune checkpoint inhibitors (ICI) for various solid tumors. Molecular advancements in cancers of the breast, kidney and brain have continued to propel tumor classification and precision therapy.
What’s new in molecular genetic pathology 2021: solid tumors and NGS panel selection
Guoli Chen, Patricia C. Tsang
J Pathol Transl Med. 2021;55(6):421-422.   Published online November 12, 2021
DOI: https://doi.org/10.4132/jptm.2021.09.01
  • 3,095 View
  • 195 Download
AbstractAbstract PDF
The linchpin of precision medicine is molecular genetic and genomic testing. Molecular biomarkers are important for establishing precise diagnoses and for predicting therapeutic responses that enable cancer patients to receive personalized and targeted treatment. Below are highlights of the current considerations in next generation sequencing (NGS) panel selection, and in molecular testing of solid tumors of the lung, digestive system, thyroid and soft tissue.

J Pathol Transl Med : Journal of Pathology and Translational Medicine
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