Journal of Pathology and Translational Medicine

Case Study

Hepatic small vessel neoplasm: not totally benign, not yet malignant: Madison Miranda, David Howell, Tony El Jabbour; J Pathol Transl Med. 2023;57(5):273-277. Published online August 24, 2023; DOI: https://doi.org/10.4132/jptm.2023.06.19

Abstract PDF: Hepatic small vessel neoplasm (HSVN) is a rare vascular tumor with few reports in the literature. While imaging findings may show characteristic enhancement patterns, limited available literature may not reveal the full potential for image-based diagnosis. Histologically, HSVN mimics other entities, though certain morphologic and immunohistochemical findings provide clues for diagnosis. However, HSVN still provides diagnostic challenges, especially on core biopsies with limited material for morphologic and molecular evaluation. While current recommendations are surgical resection and close observation, the long-term course of the tumor is unknown. We report a case of HSVN in a liver with additional feature of organized lymphoid aggregates necessitating additional hematopathology consultation and workup to rule out concurrent entities.

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