Skip Navigation
Skip to contents

J Pathol Transl Med : Journal of Pathology and Translational Medicine

OPEN ACCESS
SEARCH
Search

Search

Page Path
HOME > Search
3 "Hyun Hee Chu"
Filter
Filter
Article category
Keywords
Publication year
Authors
Case Study
Abdominal Fibromatosis in a Young Child: A Case Study and Review of the Literature
Hyun Hee Chu, Pyoung Han Hwang, Yeon Jun Jeong, Myoung Ja Chung
Korean J Pathol. 2013;47(5):472-476.   Published online October 25, 2013
DOI: https://doi.org/10.4132/KoreanJPathol.2013.47.5.472
  • 7,290 View
  • 38 Download
  • 3 Crossref
AbstractAbstract PDF

Fibromatoses comprise many different entities of well-differentiated fibroblastic proliferation with variable collagen production and form a firm nodular mass. Abdominal fibromatosis is distinguishable from other forms of fibromatosis because of its location and its tendency to occur in women of childbearing age during or following pregnancy. Abdominal fibromatosis in children is an extremely rare condition. A 15-month-old boy presented with an abdominal wall mass that had recently increased in size. Mass excision was perfomed. The tumor was 4.3×4.1 cm and partly circumscribed. Histologically, the tumor was composed of parallel long fascicles of spindle-cells with a uniform appearance. The edges of the resected mass were infiltrative, and the surgical margins were positive. Mitotic figures were <1/10 high power fields. No cellular atypia or necrosis was present. The tumor cells were positive for vimentin and nuclear β-catenin staining.

Citations

Citations to this article as recorded by  
  • A rare tumor of the large bowel in a young boy
    Shyam Srinivasan, Soumitra Saha
    Cancer Research, Statistics, and Treatment.2021; 4(4): 752.     CrossRef
  • Uncommon abdominal wall mass in a young boy: Desmoid tumor
    Levent Cankorkmaz, Mehmet H. Atalar, H. Reyhan Eğilmez
    Cumhuriyet Medical Journal.2018; : 811.     CrossRef
  • Lesiones ocupantes de espacio en pared abdominal (no herniaria). La visión del patólogo
    Isidro Machado, Julia Cruz, Javier Lavernia, Fernando Carbonell
    Revista Hispanoamericana de Hernia.2015; 3(3): 85.     CrossRef
Original Article
Expression of CHOP in Squamous Tumor of the Uterine Cervix
Hyun Hee Chu, Jun Sang Bae, Kyoung Min Kim, Ho Sung Park, Dong Hyu Cho, Kyu Yun Jang, Woo Sung Moon, Myoung Jae Kang, Dong Geun Lee, Myoung Ja Chung
Korean J Pathol. 2012;46(5):463-469.   Published online October 25, 2012
DOI: https://doi.org/10.4132/KoreanJPathol.2012.46.5.463
  • 7,689 View
  • 39 Download
  • 6 Crossref
AbstractAbstract PDF
Background

High-risk human papillomavirus (HR-HPV) infection and abnormal p53 expression are closely involved in carcinogenesis of squamous cell carcinoma (SqCC) of uterine cervix. Recent studies have suggested that virus-induced endoplasmic reticulum (ER) stress modulates various cell survival and cell death signaling pathways. The C/EBP homologous protein (CHOP) is associated with ER stress-mediated apoptosis and is also involved in carcinogenesis of several human cancers. We hypothesized that CHOP is involved in the carcinogenesis of uterine cervical cancer in association with HR-HPV and/or p53.

Methods

Immunohistochemistry was used to analyze CHOP and p53 protein expression of tissue sections from 191 patients with invasive cancer or preinvasive lesions of the uterine cervix (61 cases of SqCC, 66 cases of cervical intraepithelial neoplasia [CIN] III, and 64 cases of CIN I).

Results

CHOP was expressed in 59.4% of CIN I, 48.5% of CIN III, and 70.5% of SqCC cases. It was also significantly more frequent in invasive SqCC than in preinvasive lesions (p=0.042). Moreover, CHOP expression significantly correlated with HR-HPV infection and p53 expression (p=0.009 and p=0.038, respectively).

Conclusions

Our results suggest that CHOP is involved in the carcinogenesis of the uterine cervix SqCC via association with HR-HPV and p53.

Citations

Citations to this article as recorded by  
  • Expression of GRP78 and its copartners in HEK293 and pancreatic cancer cell lines (BxPC-3/PANC-1) exposed to MRI and CT contrast agents
    Ali Ahmed Azzawri, Ibrahim Halil Yildirim, Zeynep Yegin, Abdurrahim Dusak
    Nucleosides, Nucleotides & Nucleic Acids.2024; 43(5): 391.     CrossRef
  • Endoplasmic Reticulum Stress and Homeostasis in Reproductive Physiology and Pathology
    Elif Guzel, Sefa Arlier, Ozlem Guzeloglu-Kayisli, Mehmet Tabak, Tugba Ekiz, Nihan Semerci, Kellie Larsen, Frederick Schatz, Charles Lockwood, Umit Kayisli
    International Journal of Molecular Sciences.2017; 18(4): 792.     CrossRef
  • Endoplasmic reticulum stress pathway PERK‐eIF2α confers radioresistance in oropharyngeal carcinoma by activating NF‐κB
    Qiao Qiao, Chaonan Sun, Chuyang Han, Ning Han, Miao Zhang, Guang Li
    Cancer Science.2017; 108(7): 1421.     CrossRef
  • Curcumin induces ER stress-mediated apoptosis through selective generation of reactive oxygen species in cervical cancer cells
    Boyun Kim, Hee Seung Kim, Eun-Ji Jung, Jung Yun Lee, Benjamin K. Tsang, Jeong Mook Lim, Yong Sang Song
    Molecular Carcinogenesis.2016; 55(5): 918.     CrossRef
  • Down-regulation of C/EBP homologous protein (CHOP) expression in gastric cardia adenocarcinoma: Their relationship with clinicopathological parameters and prognostic significance
    Xiao-Juan Zhu, She-Gan Gao, San-Qiang Li, Zhen-Guo Shi, Zhi-Kun Ma, Shan-Shan Zhu, Xiao-Shan Feng
    Clinics and Research in Hepatology and Gastroenterology.2015; 39(3): 391.     CrossRef
  • MG289 in <i>Mycoplasma genitalium</i> Enhances Microbial Invasion and Bacterial Persistence in Benign Human Prostate Cells
    Wasia Rizwani, Leticia Reyes, Jeongsoon Kim, Steve Goodison, Charles J. Rosser
    Open Journal of Urology.2013; 03(06): 232.     CrossRef
Case Report
Papillary Carcinoma of Thyroid Metastatic to Adenocarcinoma In Situ of Lung: Report of an Unusual Case
Kyoung Min Kim, Yo Na Kim, Hyun Hee Chu, Heung Yong Jin, Min Ho Kim, Myoung Ja Chung
Korean J Pathol. 2012;46(3):282-286.   Published online June 22, 2012
DOI: https://doi.org/10.4132/KoreanJPathol.2012.46.3.282
  • 7,079 View
  • 50 Download
  • 6 Crossref
AbstractAbstract PDF

The tumor-to-tumor metastasis is a rare event. The lung tumors are the most common donor tumors in tumor-to-tumor metastasis, but are exceedingly rare as a recipient. Here, we report a case of papillary thyroid carcinoma (PTC) metastasizing to adenocarcinoma in situ (AIS, formerly bronchioloalveolar carcinoma) of the lung in a 44-year-old woman who underwent total thyroidectomy for PTC 8 years ago. To the best of our knowledge, the present case is the first case reporting on PTC metastasized to AIS. A review of the relevant literature is presented.

Citations

Citations to this article as recorded by  
  • A case of colorectal cancer with intratumoral metastasis to primary lung cancer
    Yasushi Cho, Mitsuhito Kaji, Shunsuke Nomura, Yusuke Motohashi, Masaaki Sato, Motoya Takeuchi
    The Journal of the Japanese Association for Chest Surgery.2021; 35(5): 576.     CrossRef
  • Tumor-to-tumor metastasis: metastatic invasive lobular carcinoma of the breast within adenocarcinoma of the lung
    Myoung Jae Kang, Ae Ri An, Myoung Ja Chung, Kyoung Min Kim
    Journal of Pathology and Translational Medicine.2020; 54(2): 188.     CrossRef
  • Metastatic Renal Cell Neoplasm Within a Papillary Thyroid Carcinoma as Incidental Finding in an Asymptomatic Patient: a Case Report
    Maria-Rosa Bella-Cueto, Mireia Pascua-Solé, Albert Cano-Palomares, M. Àngels Cabezuelo-Hernandez, Maria-Rosa Escoda-Giralt, Santiago Barcons-Vilaplana, Paula Serret-Miralles, Carmen Caral-Vanaclocha, Xavier Guirao-Garriga, Joan Prats-Lopez, Meritxell Meda
    SN Comprehensive Clinical Medicine.2020; 2(7): 978.     CrossRef
  • A Rare Case of Tumor-to-Tumor Metastasis of Thyroid Papillary Carcinoma within a Pulmonary Adenocarcinoma
    Taebum Lee, Yoon Jin Cha, Sangjeong Ahn, Joungho Han, Young Mog Shim
    Journal of Pathology and Translational Medicine.2015; 49(1): 78.     CrossRef
  • Tumour-to-tumour metastasis from papillary thyroid carcinoma withBRAFmutation to lung adenocarcinoma withEGFRmutation: the utility of mutation-specific antibodies
    Yuki Katsuya, Akihiko Yoshida, Shun-ichi Watanabe, Koji Tsuta
    Histopathology.2015; 67(2): 262.     CrossRef
  • Pulmonary metastasis of a papillary thyroid carcinoma and primary lung adenocarcinoma: two coincident carcinomas at the same location
    Liyan Xue, Zhonghua Luan, Ying Liu, Shuangmei Zou, Jun Jiang, Ning Wu, Ning Lu, Dongmei Lin
    Diagnostic Pathology.2013;[Epub]     CrossRef

J Pathol Transl Med : Journal of Pathology and Translational Medicine
TOP