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- Ovarian Gynandroblastoma with a Juvenile Granulosa Cell Tumor Component in a Postmenopausal Woman: A Case Report and Literature Review
- Nu Ri Jang, Dae Hyung Lee, Eun Jung Jang, Young Kyung Bae, Jina Baek, Min Hye Jang
- J Pathol Transl Med. 2018;52(5):344-348. Published online July 17, 2018
- DOI: https://doi.org/10.4132/jptm.2018.06.28
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- 2 Web of Science
- 4 Crossref
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Abstract
PDF - Gynandroblastoma is an extremely rare sex cord-stromal tumor with both female (granulosa cell tumor) and male (Sertoli-Leydig cell tumor) elements. Juvenile granulosa cell tumors are also very rare and are so named because they usually occur in children and adolescents. A 71-year-old woman with right upper quadrant abdominal pain visited our hospital. Pelvic computed tomography showed a large multilocular cystic mass, suspected to be of ovarian origin. We performed a total abdominal hysterectomy (total abdominal hysterectomy was performed) with bilateral salpingooophorectomy. A 13-cm multilocular cystic mass with serous fluid was observed in her right ovary. Upon microscopic examination, the solid component of the mass showed both Sertoli-Leydig cell and juvenile granulosa cell differentiation, which we diagnosed as gynandroblastoma. Gynandroblastoma with a juvenile granulosa cell tumor component is extremely rare and, until now, only six cases have been reported in the English literature. We report the first gynandroblastoma with a juvenile granulosa cell tumor component diagnosed in an elderly patient, along with a literature review.
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Citations
Citations to this article as recorded by
- Case of Gynandroblastoma of the Ovary with Raised AFP and Associated DICER 1 Mutation
Dipak Limbachiya, Rajnish Tiwari, Rashmi Kumari, Priti Trivedi
The Journal of Obstetrics and Gynecology of India.2024;[Epub] CrossRef - Ovarian cancer in children and adolescents: A unique clinical challenge
Marina Jakimovska Stefanovska, Aleksandar Celebic, Jean Calleja-Agius, Kristina Drusany Staric
European Journal of Surgical Oncology.2024; : 108785. CrossRef - Ovarian Gynandroblastoma with a Juvenile Granulosa Cell Tumor Component in a Postmenopausal Woman
Soohyun Hwang, Byoung-Gie Kim, Sang Yong Song, Hyun-Soo Kim
Diagnostics.2020; 10(8): 537. CrossRef - Clinical and histological criteria for sex cord ovarian stromal tumors
A. М. Beishembaev, K. I. Zhordania
Obstetrics, Gynecology and Reproduction.2020; 14(3): 261. CrossRef
- Case of Gynandroblastoma of the Ovary with Raised AFP and Associated DICER 1 Mutation
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