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Case Report
Childhood Asymmetry Labium Majus Enlargement.
Mi Jin Gu, Sang Yoon Kim
Korean J Pathol. 2011;45(5):529-531.
DOI: https://doi.org/10.4132/KoreanJPathol.2011.45.5.529
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AbstractAbstract PDF
Childhood asymmetry labium majus enlargement (CALME) is a disctinctive clinicopathologic entity of pre- and early puberty first described in 2005. It is defined as an expansion of normal soft tissues of the vulva. Although CALME is not a rare lesion, it has been called lipoma, fibroma, hamartoma, and fibrous hyperplasia. CALME is not a true neoplasm and is a physiologic growth in response to hormone. It may tend to resolve spontaneously and recur after surgical resection. We report four cases of CALME with a review of the literature. To the best of the knowledge, this is the first Korean report.

Citations

Citations to this article as recorded by  
  • Keep CALME (childhood asymmetry labium majus enlargement) and follow up
    Andrea Sechi, Annalisa Patrizi, Giulio Vara, Rita Golfieri, Iria Neri
    JDDG: Journal der Deutschen Dermatologischen Gesellschaft.2021; 19(9): 1276.     CrossRef
  • Bei CALME (childhood asymmetry labium majus enlargement): die Ruhe bewahren und nachverfolgen
    Andrea Sechi, Annalisa Patrizi, Giulio Vara, Rita Golfieri, Iria Neri
    JDDG: Journal der Deutschen Dermatologischen Gesellschaft.2021; 19(9): 1276.     CrossRef
  • Childhood Asymmetry Labium Majus Enlargement (CALME): Description of Two Cases
    Cristina Salvatori, Ilaria Testa, Marco Prestipino, Maria Elena Laurenti, Sara Riccioni, Giuseppe Di Cara, Nicola Principi, Susanna Esposito, Mirko Bertozzi
    International Journal of Environmental Research and Public Health.2018; 15(7): 1525.     CrossRef
  • Childhood asymmetrical labium majus enlargement sonographic and MR imaging appearances
    Ami Gokli, Jeremy Neuman, Ruby Lukse, June Koshy, Fanyi Kong, Tal Laor
    Pediatric Radiology.2016; 46(5): 674.     CrossRef

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