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- Case Report Childhood Asymmetry Labium Majus Enlargement.
- Mi Jin Gu, Sang Yoon Kim
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Journal of Pathology and Translational Medicine 2011;45(5):529-531
DOI: https://doi.org/10.4132/KoreanJPathol.2011.45.5.529
1Department of Pathology, Daegu Fatima Hospital, Daegu, Korea. gmjap@fatima.or.kr
2Department of Surgery, Daegu Fatima Hospital, Daegu, Korea.
2Department of Surgery, Daegu Fatima Hospital, Daegu, Korea.
Abstract
Childhood asymmetry labium majus enlargement (CALME) is a disctinctive clinicopathologic entity of pre- and early puberty first described in 2005. It is defined as an expansion of normal soft tissues of the vulva. Although CALME is not a rare lesion, it has been called lipoma, fibroma, hamartoma, and fibrous hyperplasia. CALME is not a true neoplasm and is a physiologic growth in response to hormone. It may tend to resolve spontaneously and recur after surgical resection. We report four cases of CALME with a review of the literature. To the best of the knowledge, this is the first Korean report.
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