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- A standardized pathology report for gastric cancer: 2nd edition
- Young Soo Park, Myeong-Cherl Kook, Baek-hui Kim, Hye Seung Lee, Dong-Wook Kang, Mi-Jin Gu, Ok Ran Shin, Younghee Choi, Wonae Lee, Hyunki Kim, In Hye Song, Kyoung-Mee Kim, Hee Sung Kim, Guhyun Kang, Do Youn Park, So-Young Jin, Joon Mee Kim, Yoon Jung Choi, Hee Kyung Chang, Soomin Ahn, Mee Soo Chang, Song-Hee Han, Yoonjin Kwak, An Na Seo, Sung Hak Lee, Mee-Yon Cho
- J Pathol Transl Med. 2023;57(1):1-27. Published online January 15, 2023
- DOI: https://doi.org/10.4132/jptm.2022.12.23
- 9,749 View
- 1,045 Download
- 8 Web of Science
- 8 Crossref
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Abstract
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Supplementary Material - The first edition of ‘A Standardized Pathology Report for Gastric Cancer’ was initiated by the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists and published 17 years ago. Since then, significant advances have been made in the pathologic diagnosis, molecular genetics, and management of gastric cancer (GC). To reflect those changes, a committee for publishing a second edition of the report was formed within the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists. This second edition consists of two parts: standard data elements and conditional data elements. The standard data elements contain the basic pathologic findings and items necessary to predict the prognosis of GC patients, and they are adequate for routine surgical pathology service. Other diagnostic and prognostic factors relevant to adjuvant therapy, including molecular biomarkers, are classified as conditional data elements to allow each pathologist to selectively choose items appropriate to the environment in their institution. We trust that the standardized pathology report will be helpful for GC diagnosis and facilitate large-scale multidisciplinary collaborative studies.
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Citations
Citations to this article as recorded by
- Genomic and Transcriptomic Characterization of Gastric Cancer with Bone Metastasis
Sujin Oh, Soo Kyung Nam, Keun-Wook Lee, Hye Seung Lee, Yujun Park, Yoonjin Kwak, Kyu Sang Lee, Ji-Won Kim, Jin Won Kim, Minsu Kang, Young Suk Park, Sang-Hoon Ahn, Yun-Suhk Suh, Do Joong Park, Hyung Ho Kim
Cancer Research and Treatment.2024; 56(1): 219. CrossRef - Microscopic tumor mapping of post-neoadjuvant therapy pancreatic cancer specimens to predict post-surgical recurrence: A prospective cohort study
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Pathology - Research and Practice.2024; 263: 155628. CrossRef - Pathological Interpretation of Gastric Tumors in Endoscopic Submucosal Dissection
Jung Yeon Kim
Journal of Digestive Cancer Research.2023; 11(1): 15. CrossRef - Histopathology of Gastric Cancer
Baek-hui Kim, Sung Hak Lee
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2023; 23(2): 143. CrossRef - Endoscopic submucosal dissection hands-on training with artificial mucosal layer EndoGEL
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- Genomic and Transcriptomic Characterization of Gastric Cancer with Bone Metastasis
Brief Case Report
- Metastatic gastric cancer of the testis diagnosed through urine cytology
- Mee Sook Roh, Song-Hee Han
- J Pathol Transl Med. 2021;55(4):303-305. Published online June 1, 2021
- DOI: https://doi.org/10.4132/jptm.2021.04.19
- 2,739 View
- 83 Download
- 1 Web of Science
- 1 Crossref
Original Article
- Mesothelin Expression in Gastric Adenocarcinoma and Its Relation to Clinical Outcomes
- Song-Hee Han, Mee Joo, Hanseong Kim, Sunhee Chang
- J Pathol Transl Med. 2017;51(2):122-128. Published online February 15, 2017
- DOI: https://doi.org/10.4132/jptm.2016.11.18
- 7,428 View
- 168 Download
- 17 Web of Science
- 15 Crossref
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Abstract
PDF
- Background
Although surgical resection with chemotherapy is considered effective for patients with advanced gastric cancer, it remains the third leading cause of cancer-related death in South Korea. Several studies have reported that mesothelial markers including mesothelin, calretinin, and Wilms tumor protein 1 (WT1) were positive in variable carcinomas, associated with prognosis, and were evaluated as potential markers for targeted therapy. The aim of this study was to assess the immunohistochemical expression of mesothelial markers (mesothelin, calretinin, and WT1) in gastric adenocarcinoma and their relations to clinocopathological features and prognosis. Methods: We evaluated calretinin, WT1, and mesothelin expression by immunohistochemical staining in 117 gastric adenocarcinomas. Results: Mesothelin was positively stained in 30 cases (25.6%). Mesothelin expression was related to increased depth of invasion (p = .002), lymph node metastasis (p = .013), and presence of lymphovascular (p = .015) and perineural invasion (p = .004). Patients with mesothelin expression had significantly worse disease-free survival rate compared with that of nonmesothelin expression group (p = .024). Univariate analysis showed that mesothelin expression is related to short-term survival. None of the 117 gastric adenocarcinomas stained for calretinin or WT1. Conclusions: Mesothelin expression was associated with poor prognosis. Our results suggest that mesothelin-targeted therapy should be considered as an important therapeutic alternative for gastric adenocarcinoma patients with mesothelin expression. -
Citations
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Brief Case Report
- Malakoplakia Affecting the Umbilical Cord
- Song-Hee Han, Mee Joo, Sunhee Chang, Han-Seong Kim
- J Pathol Transl Med. 2015;49(2):177-179. Published online March 12, 2015
- DOI: https://doi.org/10.4132/jptm.2015.02.04
- 8,601 View
- 44 Download
- 3 Crossref
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Citations
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