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The Korean Journal of Pathology 1992;26(5): 504-509.
Embryonal Sarcoma of the Liver with Chondrosarcomatous Differentiation: A case report.
Woo Hee Jung, Hyunee Yim, Ho Guen Kim, Chan Il Park, Ki Keun Oh, Seung Hoon Choi
1Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
2Department of Radiology, Yonsei University College of Medicine, Seoul, Korea.
3Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
ABSTRACT
Embryonal sarcomas of the liver, often called undifferentiated sarcomas or malignant mesenchymomas, are extremely rare tumors that occur chiefly in children with poor prognosis and uncertain histogenesis. Histologically, tumor cells are stellate or spindle shaped, loosely arranged in edematous or myxoid pattern alternating with highly cellular zones and do not show evidence of differentiation. Ultrastructural and immunohistochemical studies by previous investigators indicate that the neoplastic cells are mostly primitive mesenchymal cell which occasionally differentiate to fibroblasts, lipoblasts, histiocytes and smooth muscle cells via intermediate cell types. The authors experienced a case of 6-year old boy who presented with an enlarging abdominal mass of the liver which revealed typical histological and ultrastructural features of embryonal sarcoma with focal areas of unusual chondrosarcomatous differentiation.
Key Words: Embryonal sarcoma; Liver; Electron microscopy; Immunohistochemistry