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The Korean Journal of Pathology 1994;28(4): 405-408.
Malignant Brenner Tumor: Report of a case.
Kyeong Mee Park, So Young Park, Yeon Lim Suh
Department of Pathology, Seoul Paik Hospital, College of Medicine, Inje University, Seoul, Korea.
Brenner tumors constitute about l.5~2.5% of all primary ovarian neoplasms and are almost always benign. It appears to derive from the surface epithelium of the ovary which undergoes metap1asia to form the urothelial-like components. we experienced a case of malignant Brenner tumor with adenocarcinoma and squamous cell carcinoma patterns in a 57-year-old woman. It was partly cystic tumor and contained a 4cm-sized gray yellow, lobulated or papillary solid mass, projecting from the cystic wall. Ultrastructurally, the solid mass was composed of malignant urothelial-like cells with focal glandular differentiation.
Key Words: Malignant Brenner tumor; Ovary; Glandulatr Differentiation