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The Korean Journal of Cytopathology 1990;1(1): 98-102.
간아세포종의 세침흡인 세포학적 소견 -2예 증례보고-
박영년, 이광길, 박찬일
연세대학교 의과대학 병리학교실
Fine Needle Aspiration Cytology of Hepatoblastoma: Report of Two Cases.
Young Nyun Park, Kwang Gil Lee, Chan II Park
Department of Pathology, Yonsei University College of Medicine, Korea.
Hepatoblastoma(HB) is a rare embryonic malignant tumor of the liver. Most morphological studies on HB have limited to the histological characteristics and only 3 cases of HB have been described in the cytology literature. We present 2 cases of HB occurring in children aged 1 year and 3 years, respectively. The distinctive cytologic features of fine needle aspiration of HB were clusters of tumor cells showing acinar and trabecular pattern, smaller tumor cells with a high nuclear-cytoplasmic ratio and hyperchromatic nuclei having prominent nucleoli, and the presence of extramedullary hematopoiesis and osteoid material. These features were also found in the cell block and the biopsy specimen, and appeared very useful in the differentiation of HB from hepatocellular carcinoma.
Key Words: Hepatoblastoma; Aspiration cytology; Hepatocellular carcinoma