Abstract

Rheum coreanum Nakai(R.C.N.) has been known to possess phytohemoagglutinin activity. This experimental study is undertaken to evaluate whether R.C.N. has effect on hematopoietic activity in rabbit. Each rabbit of experimental group was injected 1.0ml of R.C.N. extract intravenously just after bleeding, and studied peripheral blood in R.B.C. count, hematocrit, hemoglobin, reticulocyte count, total W.B.C. count, Iymphocyte and granulocyte count. The result obtained are as follow : 1. Interval of recovery in erythrocytic series was shortened by R.C.N. injection after bleeding. 2. Higher level of peripheral leukocyte count in early stage was noted by R.C.N. injection after bleeding. 3. Higher level of peripheral leukocyte count was due to increased lymphocyte count. R.C.N. seems to possess activities to stimulate the bone marrow hematopoiesis and the blastoid transformation of lymphocytes.